Biggest hurdle to just experiment by randomly crispr-editing in humans are ethical, as a society the majority does not want a repeat of experiments similar to Mengeles twins.
Even though I would love to edit myself to be able to digest lignin and cellulose

If Im honest I just wish for humanity to be able to treat chromosome issues and lethal fetal issues.
Let trendy transhumanism and cellulose digestion stay on the pages of fiction. I used Mengele as the worst breaker of ethics and horrible practises I could think of